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Acute kidney injury in adults aged 60 years or older hospitalized with COVID-19 and association with mortality

dc.contributor.authorIngrid Ardisson Colodete
dc.contributor.authorCaroline Delboni Nascimento
dc.contributor.authorSarah de Jesus Francisco
dc.contributor.authorManoela Morgado Horta Barros
dc.contributor.authorJúlia Magalhães Monteiro
dc.contributor.authorJúlia Andrade Rodrigues Alves
dc.contributor.authorCaroline Maffei Spinassé
dc.contributor.authorCaroline Tessinari Pupim
dc.contributor.authorJulia Almenara Ribeiro Vieira
dc.contributor.authorRenato Lirio Morelato
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.contributor.otherEscola Superior de Ciências, Santa Casa de Misericórdia de Vitória – Vitória (ES), Brazil.
dc.date.accessioned2025-10-09T04:58:28Z
dc.date.available2025-10-09T04:58:28Z
dc.date.issued01-11-2024
dc.identifier.urihttps://cdn.publisher.gn1.link/ggaging.com/pdf/v18e0000152.pdf
dc.identifier.urihttp://digilib.fisipol.ugm.ac.id/repo/handle/15717717/40859
dc.description.abstractObjective: To analyze the presence of acute kidney injury (AKI) in hospitalized older patients with COVID-19 and its association with hospital mortality. Methods: This was a retrospective observational case-control study of patients over 60 years of age hospitalized from April 01, 2020, to April 30, 2021, at a ward or intensive care unit (ICU) dedicated to COVID-19. The severity of AKI was stratified according to the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Binary logistic regression was used to determine the association of mortality in models with and without adjustment for previous comorbidities as risk factors. Results: Of 897 patients aged 19–107 years hospitalized with COVID-19, 398 aged ≥ 60 years were included. AKI was observed in 220 patients (55.27%), with stages 1, 2, and 3 in 25.87%, 5.52%, and 23.86%, respectively. Dialysis was required in 73 patients with AKI (33.18%), most of them were at stage 3 (91.89%). Fifty-four patients on dialysis died (73.97%). Increased AKI severity was associated with mortality even after removing the influence of associated risk factors (odds ratios 1.78, 2.35, and 3.51 at stages 1, 2, and 3, respectively). Conclusion: AKI was highly common in patients aged 60 years or older hospitalized with COVID-19, and its severity showed a progressive association with hospital mortality.
dc.language.isoEN
dc.publisherBrazilian Society of Geriatrics and Gerontology
dc.subject.lccNursing
dc.titleAcute kidney injury in adults aged 60 years or older hospitalized with COVID-19 and association with mortality
dc.typeArticle
dc.description.keywordsacute kidney injury
dc.description.keywordscovid-19
dc.description.keywordshospital mortality
dc.description.keywordsaged
dc.description.pages1-6
dc.description.doi10.53886/gga.e0000152_EN
dc.title.journalGeriatrics, Gerontology and Aging
dc.identifier.e-issn2447-2123
dc.identifier.oaioai:doaj.org/journal:db7bbc7a5fb249ffbf4ef46f90b15e69


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