Show simple item record

Influence of high-bromine poultry products on clinical-biochemical blood parameters of white rats

dc.contributor.authorY. M. Koreneva
dc.contributor.authorO. L. Orobchenko
dc.contributor.authorM. Y. Romanko
dc.contributor.authorN. G. Malova
dc.contributor.authorR. M. Sachuk
dc.contributor.authorB. V. Gutyj
dc.contributor.authorM. L. Radzykhovskyi
dc.contributor.otherInstitute of Experimental and Clinical Veterinary Medicine
dc.contributor.otherInstitute of Experimental and Clinical Veterinary Medicine
dc.contributor.otherInstitute of Experimental and Clinical Veterinary Medicine
dc.contributor.otherV. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine
dc.contributor.otherRivne State University for the Humanities
dc.contributor.otherStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies
dc.contributor.otherNational University of Life and Environmental Sciences of Ukraine
dc.date.accessioned2024-10-01T08:15:32Z
dc.date.available2025-10-02T03:02:32Z
dc.date.issued01-03-2023
dc.identifier.issn-
dc.identifier.urihttps://medicine.dp.ua/index.php/med/article/view/866
dc.description.abstractBromine content in fodder and water for laying chickens in Ukraine gradually increasing, thereby accumulating in the poultry production (eggs and meat): according to the data, intake of bromine with chicken eggs in 2020 has almost doubled, compared with 2016. Taking into account the ability of bromine to accumulate and the scales of consumption of poultry products, it is relevant to study the effects of high bromine concentration on the level of thyroid hormones and clinical-biochemical parameters of blood of white rats. At the laboratory of Toxicological Monitoring of the National Scientific Center the Institute of Experimental and Clinical Veterinary Medicine and the Department of Experimental Pharmacology and Toxicology of the State Institution V.Y. Danylevskyi Institute of Problems of Endocrine Pathology of the National Academy of Medical Sciences of Ukraine, we carried out studies on white outbred male rats (n = 144). The diet of experimental groups was supplemented with eggs and meat containing high bromine concentration. We determined increase in the coefficients of liver weight and decrease in the coefficients of lung weight in the experimental rats. Moreover, we determined changes in the biochemical blood profile, in particular: after egg consumption, there occurred 20.0–22.0% decrease in the enzymatic activity of alanine aminotransferase, 23.0–48.4% in the activity of aspartate aminotransferase, and on average 21.3% decrease in alkaline phosphatase, compared with the control; after meat consumption, the level of total proteins decreased by 8.6%, glucose by 12.2–14.5%, also there were 13.8–18.5% decrease in the activity of alanine aminotransferase and 12.1–83.0% increase in the activity of aspartate aminotransferase on the 28th day, and 23.2–35.3% decrease in the activity of alkaline phosphatase. After the intake of both poultry products, the blood serum of animals was observed to have decrease in the level of overall thyroxine and overall triiodothyronine (1.3 times on average, depending on the period of study). The results of the studies can help in prediction and timely alleviation of the negative impact of poultry products with high bromine content on the human organism.
dc.format-
dc.language.isoEN
dc.publisherOles Honchar Dnipro National University
dc.relation.uri['https://managementscience.fa.ru', 'https://managementscience.fa.ru/jour/about/submissions', 'https://managementscience.fa.ru/jour/about/editorialPolicies#focusAndScope']
dc.rightsCC BY
dc.subject['performance management', 'state and municipal management', 'project management', 'efficiency assessment', 'Management. Industrial management', 'HD28-70']
dc.subject.lccScience
dc.titleInfluence of high-bromine poultry products on clinical-biochemical blood parameters of white rats
dc.typeArticle
dc.description.keywordseggs; meat; hepatotoxycity; hypothyreosis; aminotransferases; alkaline phosphatase; thyroid hormones
dc.description.pages125-130
dc.description.doi10.15421/022319
dc.title.journalRegulatory Mechanisms in Biosystems
dc.identifier.e-issn2520-2588
dc.identifier.oaioai:doaj.org/journal:bef5f313f82d42c8b37e2b6bb33739fe
dc.journal.infoVolume 14, Issue 1


This item appears in the following Collection(s)

Show simple item record