| dc.contributor.author | Jun Chen | |
| dc.contributor.author | Yingwen Lin | |
| dc.contributor.author | Zhonghua Teng | |
| dc.contributor.author | Zhibin Lin | |
| dc.contributor.author | Junrui Li | |
| dc.contributor.author | Qingchun Zeng | |
| dc.date.accessioned | 2024-04-14T16:00:08Z | |
| dc.date.available | 2025-10-02T03:11:50Z | |
| dc.date.issued | 01-03-2024 | |
| dc.identifier.issn | - | |
| dc.identifier.uri | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2024.0021 | |
| dc.description.abstract | Objective: Methylmalonic acid (MMA) buildup has recently been suggested to contribute to the onset of both age-related conditions and cardiovascular disorders. This research was aimed at examining the link between MMA and abdominal aortic calcification (AAC). Methods: Data from the 2013–2014 National Health and Nutrition Examination Survey (NHANES) were analyzed. Serum MMA levels were determined through LC-MS/MS, and MMA levels 250 nmol/L or above were considered high. Dual-energy X-ray absorptiometry was used to assess the presence of AAC. Logistic regression analysis was performed after propensity score matching (PSM) to study the relationship between MMA and AAC. Results: A total of 2483 participants were involved in this study. To eliminate large differences between the AAC and non-AAC groups, 1:1 PSM was performed. Logistic regression analysis indicated that participants with high MMA levels had a significantly greater likelihood of experiencing AAC than those with low MMA levels (OR: 1.38, 95% CI: 1.01–1.90, P = 0.046). No statistically interaction effects between AAC and BMI or the estimated glomerular filtration rate (eGFR) were observed in subgroup analyses. Conclusion: Our study indicated a significant association between high serum MMA levels and AAC incidence. | |
| dc.format | - | |
| dc.language.iso | EN | |
| dc.publisher | Compuscript Ltd | |
| dc.relation.uri | ['http://psyjournals.ru/en/social_psy/authorinstructions/', 'http://psyjournals.ru/en/social_psy/mission/', 'http://psyjournals.ru/en/social_psy/index.shtml'] | |
| dc.rights | CC BY-NC | |
| dc.subject | ['social psychology', 'sociology', 'methodology', 'Psychology', 'BF1-990'] | |
| dc.subject.lcc | Diseases of the circulatory (Cardiovascular) system | |
| dc.title | Association between Methylmalonic Acid and Abdominal Aortic Calcification in Adults: A Cross-Sectional Study | |
| dc.type | Article | |
| dc.description.pages | - | |
| dc.description.doi | 10.15212/CVIA.2024.0021 | |
| dc.title.journal | Cardiovascular Innovations and Applications | |
| dc.identifier.e-issn | 2009-8782 | |
| dc.identifier.oai | oai:doaj.org/journal:14551d1b0a044bdbbe1ee9ba9bc42dd7 | |
| dc.journal.info | Volume 9, Issue 1 | |
