Show simple item record

Ultrasound assisted extraction and liposome encapsulation of olive leaves and orange peels: How to transform biomass waste into valuable resources with antimicrobial activity

dc.contributor.authorGiuliana Prevete
dc.contributor.authorLoïc G. Carvalho
dc.contributor.authorMaria del Carmen Razola-Diaz
dc.contributor.authorVito Verardo
dc.contributor.authorGiovanna Mancini
dc.contributor.authorAlberto Fiore
dc.contributor.authorMarco Mazzonna
dc.contributor.otherDepartment of Chemistry and Technologies of Drug, Sapienza University of Rome, P.le Aldo Moro, 5, 00185 Rome, Italy; CNR-Institute for Biological Systems (ISB), Area della Ricerca di Roma 1, Via Salaria Km 29,300, 00015 Monterotondo, Italy; Corresponding authors at: Department of Chemistry and Technologies of Drug, Sapienza University of Rome, P.le Aldo Moro, 5, 00185 Rome, Italy (G. Prevete).
dc.contributor.otherSchool of Applied Science, Division of Engineering and Food Science University of Abertay, Bell Street, DD1 1HG Dundee, Scotland, UK
dc.contributor.otherDepartment of Nutrition and Food Science, University of Granada, Campus of Cartuja s/n, 18071 Granada, Spain; Institute of Nutrition and Food Technology ‘José Mataix’, Biomedical Research Centre, University of Granada, Avda. del Conocimiento s/n., 18100 Armilla, Granada, Spain
dc.contributor.otherDepartment of Nutrition and Food Science, University of Granada, Campus of Cartuja s/n, 18071 Granada, Spain; Institute of Nutrition and Food Technology ‘José Mataix’, Biomedical Research Centre, University of Granada, Avda. del Conocimiento s/n., 18100 Armilla, Granada, Spain
dc.contributor.otherCNR-Institute for Biological Systems (ISB), Area della Ricerca di Roma 1, Via Salaria Km 29,300, 00015 Monterotondo, Italy
dc.contributor.otherSchool of Applied Science, Division of Engineering and Food Science University of Abertay, Bell Street, DD1 1HG Dundee, Scotland, UK; Corresponding authors at: Department of Chemistry and Technologies of Drug, Sapienza University of Rome, P.le Aldo Moro, 5, 00185 Rome, Italy (G. Prevete).
dc.contributor.otherCNR-Institute for Biological Systems (ISB), Area della Ricerca di Roma 1, Via Salaria Km 29,300, 00015 Monterotondo, Italy
dc.date.accessioned2024-01-17T04:15:29Z
dc.date.accessioned2025-10-08T08:22:33Z
dc.date.available2025-10-08T08:22:33Z
dc.date.issued01-01-2024
dc.identifier.urihttp://digilib.fisipol.ugm.ac.id/repo/handle/15717717/35648
dc.description.abstractEvery year million tons of by-products and waste from olive and orange processing are produced by agri-food industries, thus triggering environmental and economic problems worldwide. From the perspective of a circular economy model, olive leaves and orange peels can be valorized in valuable products due to the presence of bioactive compounds such as polyphenols exhibiting beneficial effects on human health.The aqueous extracts of olive leaves and orange peels rich in phenolic compounds were prepared by ultrasound-assisted extraction. Both extracts were characterized in terms of yield of extraction, total phenolic content and antioxidant capacity; the polyphenolic profiles were deeper investigated by HPLC-MS analysis.Each extract was included in liposomes composed by a natural phospholipid, 1,2-dioleoyl-sn-glycero-3-phosphocholine, and cholesterol prepared according to the thin-layer evaporation method coupled with a sonication process.The antimicrobial activity of the extracts, free and loaded in liposomes, was investigated according to the broth macrodilution method against different strains of potential bacterial pathogenic species: Staphylococcus aureus (NCIMB 9518), Bacillus subtilis (ATCC 6051) and Enterococcus faecalis (NCIMB 775) as Gram-positive, while Escherichia coli (NCIMB 13302), Pseudomonas aeruginosa (NCIMB 9904) and Klebsiella oxytoca (NCIMB 12259) as Gram-negative.The encapsulation of olive leaves extract in liposomes enhanced its antibacterial activity against S. aureus by an order of magnitude.
dc.language.isoEN
dc.publisherElsevier
dc.subject.lccChemistry
dc.titleUltrasound assisted extraction and liposome encapsulation of olive leaves and orange peels: How to transform biomass waste into valuable resources with antimicrobial activity
dc.typeArticle
dc.description.keywordsUltrasound assisted extraction
dc.description.keywordsOlive leaves extract
dc.description.keywordsOrange peels extract
dc.description.keywordsPolyphenols
dc.description.keywordsLiposomes
dc.description.keywordsAntibacterial activity
dc.description.doi10.1016/j.ultsonch.2024.106765
dc.title.journalUltrasonics Sonochemistry
dc.identifier.oai1184e150b6b04479bbb8a5f89d8537d7


This item appears in the following Collection(s)

Show simple item record