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Application of network pharmacology in traditional Chinese medicine for the treatment of digestive system diseases

dc.contributor.authorShihao Zheng
dc.contributor.authorShihao Zheng
dc.contributor.authorYijun Liang
dc.contributor.authorTianyu Xue
dc.contributor.authorWei Wang
dc.contributor.authorWei Wang
dc.contributor.authorSize Li
dc.contributor.authorSize Li
dc.contributor.authorPeng Zhang
dc.contributor.authorXiaoke Li
dc.contributor.authorXiaoke Li
dc.contributor.authorXu Cao
dc.contributor.authorXu Cao
dc.contributor.authorQiyao Liu
dc.contributor.authorQiyao Liu
dc.contributor.authorQiyao Liu
dc.contributor.authorWenying Qi
dc.contributor.authorWenying Qi
dc.contributor.authorYongan Ye
dc.contributor.authorYongan Ye
dc.contributor.authorXiaobin Zao
dc.contributor.authorXiaobin Zao
dc.contributor.authorXiaobin Zao
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherXiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China
dc.contributor.otherFirst Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, China
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherDongfang Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherLiver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
dc.contributor.otherKey Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China
dc.date.accessioned2024-07-17T11:36:25Z
dc.date.accessioned2025-10-08T09:07:41Z
dc.date.available2025-10-08T09:07:41Z
dc.date.issued01-07-2024
dc.identifier.urihttp://digilib.fisipol.ugm.ac.id/repo/handle/15717717/38903
dc.description.abstractWith the general improvement in living standards in recent years, people’s living habits, including their dietary habits, have changed. More people around the world do not follow a healthy diet, leading to an increase in morbidity and even mortality due to digestive system diseases, which shows an increasing trend every year. The advantage of traditional Chinese medicine (TCM) in treating digestive system diseases is evident. Consequently, the mechanisms of action of single Chinese herbs and compound Chinese medicines have become the focus of research. The research method of the network pharmacology system was highly consistent with the holistic concept of TCM, and provided a new perspective and theoretical basis for basic research on digestive system diseases. This article summarizes the common databases currently used in research on TCM. It also briefly introduces the basic methods and technologies of network pharmacology studies. It also summarizes the advancements of network pharmacology technology through a comprehensive literature search on PubMed. Based on this analysis, we further explored the role of TCM in treating digestive system diseases, including chronic gastritis, gastric cancer, ulcerative colitis, and liver cirrhosis. This study provides new ideas and references for treating digestive system diseases with TCM in the future and serves as a reference for relevant researchers.
dc.language.isoEN
dc.publisherFrontiers Media S.A.
dc.subject.lccTherapeutics. Pharmacology
dc.titleApplication of network pharmacology in traditional Chinese medicine for the treatment of digestive system diseases
dc.typeArticle
dc.description.keywordsnetwork pharmacology
dc.description.keywordsdigestive system diseases
dc.description.keywordstraditional Chinese medicine
dc.description.keywordscompounds
dc.description.keywordstargets
dc.description.doi10.3389/fphar.2024.1412997
dc.title.journalFrontiers in Pharmacology
dc.identifier.e-issn1663-9812
dc.identifier.oaioai:doaj.org/journal:5972ef77098d4e7fb4e381002099b55a


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