Show simple item record

DIPNECH: a rare cause of slow-growing pulmonary nodules in a dyspnoeic patient with a history of breast cancer

dc.contributor.authorPeter Cassar
dc.contributor.authorDione Buhagiar
dc.contributor.authorJonathan Gauci
dc.contributor.authorKyra Bartolo
dc.contributor.authorAdrian Mizzi
dc.contributor.authorAndrew Mallia
dc.contributor.authorJosef Micallef
dc.contributor.otherDepartment of Nephrology, Mater Dei Hospital, Msida, Malta
dc.contributor.otherDepartment of Internal Medicine, Mater Dei Hospital, Msida, Malta
dc.contributor.otherDepartment of Respiratory Medicine, Mater Dei Hospital, Msida, Malta
dc.contributor.otherDepartment of Respiratory Medicine, Mater Dei Hospital, Msida, Malta
dc.contributor.otherDepartment of Medical Imaging, Mater Dei Hospital, Msida, Malta
dc.contributor.otherDivision of Nuclear Medicine, Department of Medical Imaging, Mater Dei Hospital, Msida, Malta
dc.contributor.otherDepartment of Respiratory Medicine, Mater Dei Hospital, Msida, Malta
dc.date.accessioned2025-10-09T04:39:51Z
dc.date.available2025-10-09T04:39:51Z
dc.date.issued01-09-2024
dc.identifier.urihttps://www.ejcrim.com/index.php/EJCRIM/article/view/4870
dc.identifier.urihttp://digilib.fisipol.ugm.ac.id/repo/handle/15717717/40753
dc.description.abstractA middle-aged woman undergoing a computed tomography scan while being investigated for a retrosternal goitre, was found to have several solid intrapulmonary nodules of varying sizes with mosaic attenuation of lung parenchyma. After serial radiology follow-up, a radiologist with a special interest in thoracic imaging made the tentative diagnosis of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) during discussions at the local multidisciplinary team meeting. Radionuclide imaging was performed to assist in reaching a diagnosis. Uptake of DOTATATE by the pulmonary nodules on a background of mosaic attenuation pattern supported a diagnosis of DIPNECH. Potential secondary metastatic disease from previous breast malignancy confounded a possible earlier diagnosis of DIPNECH, with subsequent diagnostic imaging modalities leading to the rare diagnosis. The patient was treated symptomatically with oral steroids with no improvement, and subsequently with octreotide which significantly improved her condition.
dc.language.isoEN
dc.publisherSMC MEDIA SRL
dc.subject.lccMedicine
dc.titleDIPNECH: a rare cause of slow-growing pulmonary nodules in a dyspnoeic patient with a history of breast cancer
dc.typeArticle
dc.description.keywordsdipnech
dc.description.keywordsdiffuse idiopathic pulmonary neuroendocrine cell hyperplasia syndrome
dc.description.doi10.12890/2024_004870
dc.title.journalEuropean Journal of Case Reports in Internal Medicine
dc.identifier.e-issn2284-2594
dc.identifier.oaioai:doaj.org/journal:abc7bbf311bb44709e5375fcd6513721


This item appears in the following Collection(s)

Show simple item record